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Molecular weight is another crucial factor; as the molecular weight of HPMC increases, Tg tends to increase. This is because higher molecular weight polymers have longer chains that are entangled, leading to a more rigid structure. Additionally, the presence of plasticizers, such as glycerin or polyethylene glycol, can significantly lower the Tg of HPMC by increasing chain mobility.
hpmc glass transition temperature

HPMC is considered environmentally friendly due to its biodegradability and non-toxic nature. Derived from natural cellulose, it contributes to the sustainability of various products by reducing reliance on synthetic polymers. The production process of HPMC is also evolving towards greener methods, minimizing waste and energy consumption. However, the source of cellulose, often wood pulp, underscores the importance of sustainable forestry practices to ensure the long-term viability of HPMC production.
In the pharmaceutical sector, HPMC is widely used as a drug delivery agent. Its ability to form gels and control the release of active pharmaceutical ingredients (APIs) makes it an invaluable excipient in various formulations, including tablets, capsules, and topical creams. HPMC is particularly favored for its safety profile, as it is non-toxic and has been approved by various health authorities worldwide for use in drug products. Additionally, it helps in achieving sustained-release mechanisms, ensuring that medications are delivered over an extended period, improving patient compliance and treatment effectiveness.
hpmc powder
